AN UNTARGETED METABOLOMIC ANALYSIS OF LACTICASEIBACILLUS (L.) RHAMNOSUS, LACTOBACILLUS (L.) ACIDOPHILUS, LACTIPLANTIBACILLUS (L.) PLANTARUM AND LIMOSILACTOBACILLUS (L.) REUTERI REVEALS AN UPREGULATED PRODUCTION OF INOSINE FROM L. RHAMNOSUS

Lactic acid bacteria are considered an inexhaustible source of bioactive compounds; indeed, products from their metabolism are known to have immunomodulatory and anti-inflammatory activity.Recently, we demonstrated that Cell-Free Supernatants (CFS) obtained from Lactobacillus (L.) acidophilus, Lactiplantibacillus (L.) plantarum, Lacticaseibacillus

BackgroundDifferent histone post-translational modifications (PTMs) are crucial in the regulation of chromatin, including methylations of H3 at Lysine 4 by the MLL complex.A relevant issue is how this is causally correlated to the binding of specific transcription factors False Eyelashes (TFs) in regulatory regions.NF-Y is a TF that regulates 30% o

The growing number of renewable energy replacing conventional generators results in a loss of the reserve for frequency control in power systems, while many industrial power grids often have excess energy supply due to abundant wind and solar energy resources.This paper proposes a secondary frequency control (SFC) strategy that allows industrial po

Abstract Background Amphibians are sensitive indicators of environmental Grooming and Care conditions and show measurable responses, such as changes in phenology, abundance and range limits to local changes in precipitation and temperature regimes.Amphibians offer unique opportunities to study the important ecological and evolutionary implications

BACKGROUND:Verbal autopsy (VA) is a practical method for determining probable causes of death at the population level in places where systems for medical certification of cause of death are weak.VA methods suitable for use in routine settings, such as civil registration and vital statistics (CRVS) systems, have developed rapidly in the last decade.